Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells.
Plasmacytoid Dendritic Cells (pDCs) represent a key immune cell in the defense against viruses.Through pattern recognition receptors (PRRs), Soap these cells detect viral pathogen associated molecular patterns (PAMPs) and initiate an Interferon (IFN) response.pDCs produce the antiviral IFNs including the well-studied Type I and the more recently de